Epidemiology and prognostic factors of necrotizing fasciitis in resource-limited regions based on 119 cases.

ABSTRACT: Necrotizing fasciitis (NF) is a rare, life-threatening soft tissue infection with high amputation and mortality rates, often due to delayed diagnosis and treatment. This study analyzes the clinical characteristics and prognostic factors of NF to improve treatment strategies. A retrospective study was conducted on 119 NF patients treated at a tertiary hospital in Guangxi, China, from 2017 to 2023. Data on demographics, laboratory parameters, microbiology, treatments, and outcomes were collected and analyzed. Comparisons were made between survivors and non-survivors, and between patients with and without amputation. The predictive performance of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) was assessed using receiver operating characteristic (ROC) curve analysis. Among 11

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12304161 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature