Cost-effectiveness of one-off upper abdominal CT screening as an add-on to lung cancer screening in England.

ABSTRACT:

Background

Low-dose computed tomography (CT) screening for lung cancer is available for high-risk individuals in England. Screening simultaneously for upper abdominal conditions, including cancer, is feasible. Here, we estimate the cost-effectiveness of one-off upper abdominal CT screening, added onto lung cancer screening, based on the Yorkshire Kidney Screening Trial (YKST) feasibility study.

Methods

A multi-disease health economic model was developed. Ten cancers and abdominal aortic aneurysm (AAA) were modelled over a lifetime horizon. YKST data informed disease prevalence, resource use and screening costs. Costs, quality-adjusted life-years (QALYs) and cost-effectiveness were estimated probabilistically.

Results

Screening per person costs £70.89, produces 0.0059

SUBMITTER: Thomas C 

PROVIDER: S-EPMC12304199 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature