Clinical value of D-dimer combined with transvaginal ultrasonography in the postmenopausal population with endometrial carcinoma.

ABSTRACT: To evaluate the diagnostic value of plasma D-dimer combined with transvaginal ultrasonography for endometrial carcinoma in postmenopausal women, addressing the increasing incidence in China. This retrospective study analyzed 129 postmenopausal women (July 2021-January 2023) undergoing hysteroscopy, including 61 with endometrial carcinoma (mean age 56.5 ± 6.8 years) and 68 with benign lesions (60.2 ± 7.7 years). We assessed D-dimer levels, ultrasonographic parameters (endometrial thickness, uterine cavity occupation, blood flow signals), and postmenopausal bleeding. Diagnostic performance was evaluated using ROC curves. Multivariate analysis identified three independent predictors: intracavitary blood flow (OR 60.44, 95% CI 8.25-442.98, p < 0.001), postmenopausal bleeding (OR 5.84, 95% CI 1

SUBMITTER: Guo X 

PROVIDER: S-EPMC12304256 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature