Normal tissue outlining guidelines development for soft tissue sarcoma of the extremities.

ABSTRACT:

Introduction

Radiotherapy (RT) plans for soft tissue sarcoma of the extremities (STSE) are optimised to achieve maximum target coverage whilst avoiding high doses to weight-bearing bones and intermediate doses to the normal tissue (NT) limb corridor. Within this study, novel lower extremity NT outlining guidelines and atlas were developed based on the hypothesis that using these for RT planning may reduce RT toxicity. Usability and applicability of the guidance were also investigated.

Methods

Guidelines for NT outlining were developed. Two STSE cases were selected and a set of reference volumes was outlined on each case by one Therapeutic Radiographer/Radiation Therapist (RTT) and peer-reviewed by a consultant radiation oncologist (RO). NTs were then outlined following the g

SUBMITTER: Simoes R 

PROVIDER: S-EPMC12304711 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature