A population-based study of cause-specific mortality in First Nations Australians with cirrhosis: impact of cardiometabolic comorbidities and liver disease risk factors.

ABSTRACT:

Background

Liver disease is an important contributor to high mortality in First Nations Australians. We describe cause-specific mortality by First Nations status in people with cirrhosis.

Methods

Population-based retrospective cohort analysis of all adults with cirrhosis admitted to hospitals in the state of Queensland (2007-2022). Patients (1909 First Nations and 20,584 non-First Nations) were followed from the first admission with cirrhosis until date of death, liver transplant, or 31 December 2022, whichever came first. Multivariable Cox regression and Fine and Gray proportional subhazard models were used to assess differences in mortality according to First Nations status.

Findings

During a median follow-up of 6.9 years (IQR 3.5-11.1), 995 (52.1%) First Nations an

SUBMITTER: Bhasker V 

PROVIDER: S-EPMC12304712 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature