Motoric Cognitive Risk Syndrome Associated With Risk of Frailty and Likelihood of Reversion in Older Adults.

ABSTRACT:

Background

Motoric cognitive risk syndrome (MCR), a predementia condition, is reported to be associated with frailty. However, the associations of MCR with frailty risk and its reversibility remain unclear.

Methods

A longitudinal study was conducted of 10 809 older adults from the Health and Retirement Study in the United States. Frailty was assessed by the frailty index and reversibility was measured by transitions from frailty at baseline to non-frailty during follow-up. MCR was defined as the presence of both subjective cognitive complaints and slow gait speed in individuals without dementia or mobility disability. Multistate Markov models were performed to evaluate the effects of MCR on transitions among non-frailty, frailty and death. Cox regression models were used to

SUBMITTER: Hou D 

PROVIDER: S-EPMC12304730 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature