Six-Minute Walk Test Is Superior to Grip Strength as a Marker of Functional Recovery During Cancer Cachexia Rehabilitation.

ABSTRACT:

Background

Decline in functional independence is a defining event of cancer cachexia, and attempts at creating cachexia-specific therapies have largely failed because of the inability to identify treatments that improve functional capacity. This may be, in part, due to a lack of outcomes that are appropriate and sensitive enough to detect functional recovery. Grip strength is a frequently used outcome measure in cachexia clinical studies; however, the use of gait-based measures is now emerging. These two outcome measures have never been directly compared in the same cohort of cachexia patients regarding their ability to measure and relationship to functional independence. We hypothesize that gait-based measures more comprehensively act as a proxy measure for functional independence

SUBMITTER: Barber A 

PROVIDER: S-EPMC12304731 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature