The Association of Aortic Stenosis Severity and Symptom Status With Morbidity and Mortality.

ABSTRACT:

Background

The relationship between aortic stenosis (AS) severity, AS-related symptoms, and clinical outcomes is poorly understood.

Objectives

The purpose of this study was to evaluate whether potential AS-related symptoms at diagnosis are associated with outcomes, including death and AS-related hospitalization.

Methods

In this retrospective cohort study from a large, integrated health care system serving >4.5 M individuals, we applied validated natural language processing algorithms to echocardiogram reports to identify physician-assessed AS severity and potential AS-related symptoms (eg, chest pain, syncope, dyspnea, worsening heart failure) via diagnosis codes and natural language processing-applied physician notes. Of 602,821 adults with echocardiograms from 2010

SUBMITTER: Solomon MD 

PROVIDER: S-EPMC12304764 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature