Socioeconomic status and economic hardship attenuated the associations between early tobacco or nicotine use and brain outcomes in preadolescent children.

ABSTRACT:

Objectives

Early tobacco use (before age 11) is linked to poorer cognition and reduced cortical surface area and volume in young adolescents. This study examined how socioeconomic status (SES) factors - parental education, household income, and economic hardships - influenced these associations.

Methods

Using baseline (N=11,876) and year 3 (N=10,414) datasets from the Adolescent Brain Cognitive Development study, we assessed the impact of baseline tobacco/nicotine use initiation on cognitive scores, cortical volume, thickness, and surface area across the entire cohort and in propensity-matched subgroups. Linear mixed effects models controlled for SES and other covariates, with multiple comparison correction. Analyses were cross-sectional at baseline and longitudinal with bot

SUBMITTER: Rodriguez Rivera PJ 

PROVIDER: S-EPMC12304878 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature