Prophylactic Antibiotics Before Insertion of Tunneled Hemodialysis Catheters: A Nationwide Cohort Study.

ABSTRACT:

Rationale & objective

It is unknown whether administration of prophylactic systemic antibiotics immediately before tunneled catheter insertion can prevent early hemodialysis catheter-related bloodstream infections (HDCRBSI). We aimed to estimate the effect of systemic prophylactic antibiotics on early HDCRBSI.

Study design

An observational secondary analysis using data from the nationwide REDUcing the burden of dialysis Catheter ComplicaTIOns: a National approach trial.

Setting & participants

Adults with an incident hemodialysis catheter inserted in one of 37 Australian nephrology services from December 2016 to March 2020.

Exposure

Service-wide policy of systemic prophylactic antibiotic use before tunneled catheter insertion determined by response to a prestudy

SUBMITTER: Lazarus B 

PROVIDER: S-EPMC12304927 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature