Amyloid PET and clinical management in a diverse, cognitively impaired population: The New IDEAS Study.

ABSTRACT:

Introduction

The New Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study (NCT04426539) evaluated the association between amyloid positron emission tomography (PET) and changes in clinical management among ethnoracially diverse, clinically heterogeneous patients.

Methods

We assessed diagnosis and management plan before and 90 ± 30 days after amyloid PET among Medicare beneficiaries who met 2018 National Institute on Aging-Alzheimer's Association criteria for mild cognitive impairment (MCI) or dementia. We aimed to identify ≥ 30% change in a composite patient management endpoint (CPME; i.e., changes in Alzheimer's disease [AD]/non-AD medications, changes in counseling).

Results

Among 5757 participants (median age 75 years; 21.7% Black, 20.3% Latinx, 58.1% all o

SUBMITTER: Windon CC 

PROVIDER: S-EPMC12305457 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature