Identification of Polymeric Nanoparticles Using Strategic Peptide Sensor Configurations and Machine Learning.

ABSTRACT: Environmental pollution by miniaturized plastics such as micro- and nanoplastics continues to escalate, posing serious risks to ecosystems and human health. Therefore, there is an urgent need to detect or identify the plastics. Although the techniques for microplastics have been advanced, those for nanoplastics remain challenging owing to the difficulty of sample collection and sensing reliability. In this study, the identification of polymeric nanoparticles dispersed in water was demonstrated using peptide sensors with a microenvironment-sensitive fluorophore. The fluorescence spectra obtained from peptide sensors were different depending on the polymer species of polymeric nanoparticles. Supervised and unsupervised machine learning on the signal patterns of fluorescence intensities obtai

SUBMITTER: Hasegawa S 

PROVIDER: S-EPMC12305639 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature