Bone shape changes over two years following acute anterior cruciate ligament injury: Reconstructed vs non-reconstructed knees.

ABSTRACT:

Objective

To determine bone shape changes over two years after acute anterior cruciate ligament (ACL) injury and to compare knees treated with ACL reconstruction (ACLR) vs no ACLR.

Design

We used prospective data involving 129 young adults (46 ​% female, mean age 25 years) with recent ACL injury from a subcohort within the prospective multicenter NACOX study. Patients were treated according to Swedish guidelines with supervised rehabilitation before considering ACLR. 3D MR images obtained at baseline, 3-, 6-, 12, and 24-months post-injury were assessed for changes in the femur and tibia bone surface area using active appearance models. We used a linear mixed-effects model adjusted for age, sex, body mass index, and pre-injury Tegner physical activity level.

Results

We

SUBMITTER: Hassanlou L 

PROVIDER: S-EPMC12305710 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature