Protective effect of high-density lipoprotein in infective endocarditis patients after valve surgery.

ABSTRACT:

Introduction

Lipoproteins and insulin resistance are associated with the prognosis of cardiovascular disease, with strong evidence supporting a causal relationship for some; however, whether lipoproteins and insulin resistance have prognostic value in patients with infective endocarditis after valve surgery remains unclear.

Methods

We included 278 consecutive patients with a definite diagnosis of IE who underwent valve surgery from January 2010 to December 2022. Mortality was analyzed in relation to lipid profile and insulin resistance. Patients were divided into a higher high-density lipoprotein (＞0.905 mmol/L) group and a lower high-density lipoprotein (≤0.905 mmol/L) group based on the cutoff value of the high-density lipoprotein. A Kaplan-Meier survival analysis was cond

SUBMITTER: Zhao S 

PROVIDER: S-EPMC12305736 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature