Group B streptococcus in pregnant women and neonates in Africa: a scoping review.

ABSTRACT:

Abstract

Introduction

Group B streptococcus (GBS) affects approximately 19.7 million pregnant women, causing about 58 300 (0.3%) infant deaths globally, with highest disease burden observed in Africa. Providing a Kenyan advisory board with evidence guiding maternal GBS priority interventions, we reviewed evidence and identified gaps on determining factors, vertical transmission rates (VTR), signs and symptoms, provision of care, burden, testing, comorbidities, sequelae, and management of maternal GBS colonisation and neonatal early-onset disease (EoD) in Africa.

Methods

We searched MEDLINE, EMBASE, Web of Science and Global Index Medicus, CINAHL and SCOPUS, CENTRAL, ClinicalTrials.gov and WHO Trials Register and MedRxiv. Two independent reviewers screened studies and

SUBMITTER: Were LM 

PROVIDER: S-EPMC12306227 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature