Efficacy of non-surgical treatments for acute non-specific low back pain: protocol for systematic review and network meta-analysis of randomised controlled trials.

ABSTRACT:

Introduction

Acute low back pain (LBP) is a prevalent condition with various non-surgical treatment options, yet no comprehensive network meta-analysis has systematically compared their relative efficacy for pain and disability. This study aims to fill that gap by synthesising available evidence on the efficacy of different types of non-surgical interventions for acute LBP, such as various medications, manual therapies and education-based therapies. Our coprimary objectives are to (1) compare each active treatment to an inert reference for measures of LBP and related disability and (2) rank the efficacy of treatments.

Methods and analysis

We will conduct a systematic search across multiple databases, including grey literature, to identify randomised controlled trials evaluat

SUBMITTER: Trager RJ 

PROVIDER: S-EPMC12306272 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature