Is rotavirus aetiology in young children with acute diarrhoea associated with sociodemographic and clinical factors, including rotavirus vaccination status? A secondary cross-sectional analysis of the ABCD trial.

ABSTRACT:

Introduction

One of the leading causes of global child mortality continues to be diarrhoea where rotavirus contributed to about 24% of deaths among all diarrhoeal deaths, mostly in low-income and middle-income countries. Rotavirus vaccination programmes have contributed to the reduction of mortality from 24% to 19% in rotavirus infections among hospitalised children, but the burden of rotaviral diarrhoea remains high, especially in settings with undernutrition. We aimed to determine the association of rotaviral diarrhoea aetiology with prior vaccination, socioeconomic status and clinical factors in children to see their utility in clinical settings.

Methods

We analysed secondary data from a multicentre clinical trial on antibiotic impact in children with diarrhoea and increa

SUBMITTER: Somji S 

PROVIDER: S-EPMC12306288 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature