Association between device-based measured physical activity timing and depression risk: a prospective cohort study of UK Biobank participants.

ABSTRACT:

Introduction

Physical activity (PA) decreases the risk of mental diseases. Although PA timing has been hypothesised to affect mental health outcomes, no large-scale epidemiological cohort studies have been performed. We investigated the association between PA timing and incident depression in the general population.

Methods

A total of 89 934 European participants (62.4±7.9 years, age range: 43-79 years, 44.8% men) without a history of depression were analysed. Hourly PA levels were derived from accelerometry data and standardised for the total daily amount of PA. Participants were followed for a maximum of 8.5 years. Risks of incident depression dependent on individually standardised hourly PA level were assessed using Cox proportional-hazards models adjusted for potential c

SUBMITTER: Albalak G 

PROVIDER: S-EPMC12306291 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature