Tobacco smoking as an endocrine disrupting chemical: An assessment through biological monitoring.

ABSTRACT:

Introduction

Tobacco smoke is a mixture of endocrine disrupting chemicals (EDCs), which may accelerate biological ageing.

Methods

Within this cross-sectional study we recruited adult and adolescent subjects (2013-2014) and performed biological monitoring to clarify health end points of tobacco smoking between adolescents and adults (n=620) with exposure biomarkers, i.e. CO, urinary cotinine, t,t-muconic acid (TTMA), malondialdehyde (MDA), and obtained information of behavioral factors and tobacco addiction status in South Korea. We also analyzed the 96 SNPs for metabolism, addiction, and expression differences and compared mtDNA abnormalities in buccal and blood cells.

Results

There was an association between tobacco smoking and oxidative stress with urinary cotinine

SUBMITTER: Lee HS 

PROVIDER: S-EPMC12306452 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature