Improving social determinants of health significantly reduces AIDS incidence: a modelling study of 1.17 million individuals in Brazil.

ABSTRACT: Despite progress in addressing HIV/AIDS, the burden remains uneven, especially in low- and middle-income countries (LMICs). Social determinants of health (SDH) significantly influence HIV/AIDS. We studied the impact of SDH inequalities on AIDS incidence in Brazil, a large and diverse LMIC. We used an agent-based model (ABM) to introduce the SDH inequalities of income, education, sex and race in an HIV/AIDS model of 1 172 721 residents in 10 Brazilian state capitals. We simulated the poorest half of the population using the Cadastro Único database and calibrated our baseline models for each city with AIDS incidence from 2012 to 2019. We compared them with an alternative scenario where the effect of inequalities in SDH was removed. The difference between scenarios and subpopulations was meas

SUBMITTER: Anderle RVR 

PROVIDER: S-EPMC12306475 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature