Bacterial co-infection and secondary infection in critically ill patients with acute respiratory failure of coronavirus disease 2019.

ABSTRACT:

Objectives

The objective of the study is to understand the prevalence of bacterial co-infection and secondary infection in severe coronavirus disease 2019 (COVID-19) pneumonia in a tertiary hospital intensive care unit (ICU), the spectrum of pathogens, and the impact of these infections on clinical outcomes.

Materials and methods

Retrospective analysis of all patients with COVID-19 with acute hypoxemic respiratory failure who were admitted to the ICU requiring invasive mechanical ventilation (IMV) or high-flow nasal cannula (HFNC) from January 2021 to August 2022.

Results

Of the 123 cases, 59.3% had culture-confirmed bacterial co-infection, mostly lower respiratory tract infections (LRTIs). Patients with bacterial co-infection had higher 30-day mortality (28.8% vs. 12

SUBMITTER: Chen YT 

PROVIDER: S-EPMC12306867 | biostudies-literature | 2025 Jul-Sep

REPOSITORIES: biostudies-literature