Fibrinogen-Albumin Ratio: An Independent Recurrence Factor for Colorectal Cancer Stages II and III in a Competing Risk Model.

ABSTRACT:

Objectives

Colorectal cancer remains a major global health concern. Identifying high-risk patients is crucial for optimizing treatment strategies. The prognostic value of biomarkers, especially considering competing risks, remains unclear. We used a competing risks model to exclude the influence of non-cancer-related mortality and examined FAR as a predictor of recurrence in colorectal cancer.

Methods

This retrospective study analyzed 359 patients with stage II or III colorectal cancer from the cecum to the oral side of the peritoneal inversion, all of whom underwent curative resection at Fukui University Hospital. The primary outcome was cancer recurrence. The fibrinogen-albumin ratio (FAR) was assessed using univariate and multivariate analyses, including competing risk mo

SUBMITTER: Shimada M 

PROVIDER: S-EPMC12307011 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature