Correlation between allergic diseases and lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This meta-analysis aims to investigate the potential association between allergic diseases and lung cancer.

Methods

A systematic search was conducted in PubMed, Cochrane Library, Embase, and Web of Science databases up to October 8, 2024. Data analysis was performed using Stata 14.0, employing fixed or random effects models based on heterogeneity (p > 0.1, I² ≤ 50% or I² > 50%). Subgroup and sensitivity analyses were conducted, and publication bias was assessed.

Results

Analysis of 10 studies revealed a negative association between allergic diseases and lung cancer risk (OR: 0.75, 95% CI: 0.66-0.85, I² = 74.4%, p < 0.001). Subgroup analyses showed eczema was not statistically associated with lung cancer (OR = 0

SUBMITTER: Yang K 

PROVIDER: S-EPMC12307174 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature