The relationship between oxidative balance score, depression, and survival among adult cancer survivors in the United States.

ABSTRACT:

Background

Depression and oxidative balance score (OBS) are linked to disease risk, yet their combined effects on cancer survival remain unclear. This study assessed OBS, depression, and mortality in cancer survivors.

Methods

Utilizing a prospective, population-based cohort design, this analysis enrolled 1,455 adult cancer survivors (age ≥20 years) through the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. The OBS was related to diet and exercise, and depression was self-reported. Depressive symptomatology was measured using the established Patient Health Questionnaire-9 (PHQ-9) self-report questionnaire. Depression was defined as a total PHQ-9 score > 4, indicating the presence of depressive symptoms. A score ≤ 4 was considered to indicate no d

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12307194 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature