Disparities in Peripheral Circulatory Complication-Related Mortality in Type 2 Diabetes Mellitus Patients: A CDC Analysis (1999-2020).

ABSTRACT:

Introduction

Peripheral circulatory complication (PCC), a significant complication of type 2 diabetes mellitus (T2DM), poses a considerable mortality burden in the United States. This study aimed to analyse demographic and geographic disparities in PCC-related mortality in T2DM patients from 1999 to 2020.

Methods

Utilising the CDC WONDER database, we utilised death certificates to identify PCC-related deaths using ICD-10 Code E11.5 and calculated age-adjusted mortality rates (AAMRs) per 1,000,000 individuals. Joinpoint regression analysis was used to assess annual percent changes (APCs) in mortality rates.

Results

PCC caused 81,793 deaths. The AAMR increased from 1999 to 2004 (APC: 5.88, 95% CI: 2.44 to 12.70), followed by a decrease from 2004 to 2014 (APC: -3.70, 95%

SUBMITTER: Shahid I 

PROVIDER: S-EPMC12307238 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature