Successful reperfusion for better outcomes in medium vessel occlusion: Penumbral salvage versus infarct volume reduction.

ABSTRACT:

Background

The benefits of endovascular thrombectomy (EVT) over medical treatment for medium vessel occlusion (MeVO) remain uncertain. Understanding how vascular reperfusion leads to favorable outcomes is crucial. This study examines whether penumbra salvage and infarct volume reduction quantify EVT benefits in MeVO patients and assesses their impact on clinical improvement post-reperfusion.

Methods

We conducted a multicenter, observational study analyzing MeVO patients who underwent thrombectomy and received multimodal CT imaging from January 2020 to June 2024. EVT efficacy was evaluated by measuring follow-up infarct volume (FIV) on CT scans 24-48 h post-procedure and calculating the penumbra salvage index (PSI). PSI is the ratio of salvaged tissue volume (difference betwe

SUBMITTER: He G 

PROVIDER: S-EPMC12307323 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature