Experiences with risk-reducing mastectomy in Norwegian BRCA1/2 carriers without prior breast cancer.

ABSTRACT:

Background

BRCA1 and BRCA2 carriers without prior breast cancer have the option to undergo risk-reducing mastectomy (RRM). The aim of this study was to investigate factors associated with their decision, experiences with the process, and satisfaction with the procedure.

Materials and methods

We distributed a cross-sectional survey to 425 women aged 25-70 with a pathogenic BRCA1/2 variant. The survey collected data on sociodemographic factors, family cancer history, reasons for choosing RRM or not, experiences with the decision-making process, support from healthcare, and surgery satisfaction. Multivariate logistic regression analysis identified factors associated with the decision to undergo RRM and satisfaction with having undergone surgery.

Results

Of the 272 respon

SUBMITTER: Hyldebrandt HK 

PROVIDER: S-EPMC12307508 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature