A Bayesian network analysis of the Pfizer COVID-19 vaccine in the paediatric population.

ABSTRACT: The Pfizer COVID-19 vaccines have been associated with an increased risk of myocarditis. However, COVID-19 infection is also associated with complications. A Bayesian network (BN), informed by Australian and international data, was created to determine individual risks and benefits of the Pfizer COVID-19 vaccine in the paediatric. The risk of myocarditis between vaccine-associated, COVID-19 and background rates was compared, as well as secondary outcomes such as hospitalization, and MIS-C. At a population level, hospitalizations, intensive care admissions and MIS-C cases prevented at differing transmission rates and vaccine coverage were analyzed. The model estimated that teenage males were 4.47 times more likely to develop myocarditis from COVID-19 compared to the vaccine. Furthermore, th

SUBMITTER: Shukla T 

PROVIDER: S-EPMC12307593 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature