Network-based identification of hub transcription factors associated with benzylisoquinoline alkaloid biosynthesis in <i>Papaver somniferum</i>.

ABSTRACT: Papaver somniferum L. (Opium poppy) is one of the world's most economically valuable medicinal plants, and it is the industrial source of essential compounds such as painkillers and other pharmecutical drugs. Recently, large amounts of opium poppy transcriptome data have become accessible in public databases, consisting of data on the different tissues and ecotypes. Despite the importance of this plant, there is little information about the regulatory mechanisms involved in secondary metabolites, especially in benzylisoquinoline alkaloids (BIAs) biosynthesis at the omics level in opium poppy. Herein, we employed co-expression and co-regulation network analysis using Weighted Gene Co-expression Network Analysis (WGCNA) to infer and reveal gene interactions in opium poppy by using RNA

SUBMITTER: Eshaghi M 

PROVIDER: S-EPMC12307667 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature