Rhizobium biostimulation of blackberry modulates survival pathways in Caenorhabditis elegans across biological kingdoms.

ABSTRACT: Endophytic Rhizobium species represent promising bioinoculants for enhancing crop performance and nutritional profiles. This study investigated the impact of Rhizobium sp. CRRU65 inoculation on blackberry (Rubus sp.) plants, with emphasis on fruit phytochemical composition and cross-kingdom bioactivity. Inoculated plants exhibited a significant increase in yield and elevated levels of phenolic compounds, notably sanguiin H6 and cyanidin-3-O-glucoside, as quantified by HPLC-DAD-MS. Antioxidant functionality was evaluated using Caenorhabditis elegans under oxidative stress. Extracts from inoculated fruits significantly improved nematode survival, accompanied by transcriptional upregulation of skn-1 and hsp-16, genes involved in stress response and proteostasis. These findings demonstrate tha

SUBMITTER: Roca-Couso R 

PROVIDER: S-EPMC12307951 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature