Prevalence and Adverse Outcomes of Iron Deficiency in Heart Failure.

ABSTRACT:

Introduction/objective

Outcomes of iron deficiency (ID) in heart failure (HF) with preserved ejection fraction (HFpEF) or in samples with mixed heart failure subtypes are variably described. Hence, we investigated the prevalence and adverse outcomes of ID in a sample of mixed heart failure subtypes.

Methods

Adult patients admitted with HF over a six-month period were retrospectively studied. ID was defined as serum ferritin<100 mcg/L, or serum ferritin 100-300 mcg/L with serum transferrin saturation<20%. For each case of ID, sex- and age-matched (within five years) controls were selected. The primary outcome was the composite of all-cause mortality or readmissions up to 12 months post-index admission.

Results and discussion

Of the 245 patients admitted with HF [HFpEF:

SUBMITTER: Habeeb HA 

PROVIDER: S-EPMC12307997 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature