Sarcopenia and cardiovascular disease among adults with cardiovascular-kidney-metabolic syndrome stages 0-3: A prospective cohort study.

ABSTRACT:

Background

Substantial evidence has demonstrated the correlation between sarcopenia and cardiovascular disease (CVD). However, it remains uncertain whether this correlation exists in individuals with cardiovascular-kidney-metabolic (CKM) syndrome.

Methods

This study used data from the China Health and Retirement Longitudinal Study (CHARLS). Sarcopenia state was determined according to the Asian Working Group for Sarcopenia 2019 criteria. Muscle mass was estimated by the height-adjusted muscle mass. Cox proportional hazard models were employed to calculate the hazard ratio (HR) and 95 % confidence interval (95 % CI.

Results

A total of 7428 participants (mean age: 59.0 years; male: 47.6 %) were included in this study. Of these, non-sarcopenia, possible sarcopenia, and s

SUBMITTER: Wei Y 

PROVIDER: S-EPMC12308004 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature