High-field fMRI at 7 Tesla reveals topographic responses tuned to number in the developing human brain.

ABSTRACT: In the adult brain, hemodynamic responses to visually presented numerosities reveal receptive field-like tuning curves in topographically organized maps across association cortices. It is currently unknown whether such tuned topographic responses to numerosities can also be detected in the developing brain. Here we conducted a 7 Tesla fMRI experiment in which we presented a large set of visual dot displays to children and adults. We found that developing hemodynamic responses indeed already revealed logarithmic Gaussian tuning to quantitative information in children. Remarkably, tuning models explained comparable amounts of variance in children and adults. In most subjects, six bilateral cortical maps consistently exhibited topographic responses to numerosities. The present study goes beyo

SUBMITTER: Jeong GR 

PROVIDER: S-EPMC12308021 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature