Multimorbidity in Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Multimorbidity (the presence of multiple long-term conditions) increases the complexity of management decisions for patients presenting with acute coronary syndrome (ACS).

Objectives

The purpose of this study was to ascertain the prevalence of multimorbidity in ACS and assess its impact on clinical management and outcomes.

Methods

Medline, Web of Science, Embase, and Cochrane were searched to July 2024 for studies that reported: 1) the prevalence of multimorbidity in patients with incident ACS or 2) ACS management and/or clinical outcomes, stratified by multimorbidity status. Random-effects meta-analysis was performed to calculate pooled summary statistics and was supported by narrative synthesis.

Results

Overall, 41 studies were included. Those at l

SUBMITTER: Batty JA 

PROVIDER: S-EPMC12308028 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature