Population-based multistate modelling of peritraumatic opioid use among trauma patients from the Norwegian Trauma Registry.

ABSTRACT:

Background

Previous studies document high rates of long-term opioid use (LTU) among trauma patients, without accounting for opioid prescription doses, frequency, and medical indications. Using detailed LTU criteria, this study aimed to construct a multistate model of peritraumatic opioid use and elucidate reasons for posttraumatic LTU.

Methods

This population-based cohort study links data from the 2015-2018 cohorts in the Norwegian Trauma Registry (n=24 224) with outpatient medication prescription records from the Norwegian Prescription Database for 1 yr before and 2 yr after injury. LTU was assigned upon receiving ≥900 morphine milligram equivalents within 90 days and another opioid prescription 91-180 days after any initial prescription; it ended after 180 days without opi

SUBMITTER: Engel S 

PROVIDER: S-EPMC12308083 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature