Milk Protein Glycation Compromises Postprandial Lysine Bioavailability but does not Modulate Postprandial Muscle Protein Synthesis Rates In Vivo in Males: A Double-blind, Randomized Parallel Trial.

ABSTRACT:

Background

Industrial processing and storage of milk products can strongly increase protein glycation level. Previously, we have reported that a high protein glycation level impairs protein digestion, thereby compromising lysine bioavailability. The lower postprandial lysine availability may restrict the anabolic properties of a high glycated protein.

Objectives

The objective of this study was to assess the impact of milk protein glycation on postprandial plasma amino acid availability and subsequent postprandial muscle protein synthesis rates during recovery from a single bout of resistance-type exercise.

Methods

Forty-five recreationally active, healthy young males participated in this double-blinded, randomized parallel study. After performing a single bout of whol

SUBMITTER: van Lieshout GA 

PROVIDER: S-EPMC12308134 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature