Hemoglobin During Pregnancy Does Not Mediate the Relationship between Nutrition Supplements and Intrauterine Growth: A Secondary Data Analysis of Women First Preconception Nutrition Trial.

ABSTRACT:

Background

Nutrition supplements such as multiple micronutrient-fortified small-quantity lipid-based nutrient supplementation (SQ-LNS) consumed either before or during pregnancy have been shown to improve intrauterine growth, but the mechanisms through which the supplements improve intrauterine growth remain unclear.

Objectives

We examined whether hemoglobin (Hb) during pregnancy could be a potential mechanism through which multiple micronutrient-fortified SQ-LNS improve intrauterine growth.

Methods

We used data collected from women and newborns in a randomized controlled trial conducted in Pakistan, India, the Democratic Republic of the Congo, and Guatemala. Women were randomly assigned to consume multiple micronutrient-fortified SQ-LNS from preconception until birth

SUBMITTER: Ali SA 

PROVIDER: S-EPMC12308138 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature