Latent dimension linking functional connectivity with post-stroke deficits across multiple domains.

ABSTRACT: Stroke often leads to multiple behavioural impairments. Understanding the neural basis of these deficits is essential for elucidating the mechanisms of functional impairments and optimising therapeutic strategies for stroke patients. Although many studies have revealed that specific behavioural deficits are related to disruptions in distributed functional connectivity across brain networks, these studies typically focus on single behavioural traits, overlooking the multivariate characteristics of deficits after stroke. Recent studies have demonstrated that deficits within and across domains are highly correlated, suggesting a complex many-to-many mapping between brain and behaviour following stroke. Thus, the present study aims to identify meaningful multivariate patterns of functional con

SUBMITTER: Wu K 

PROVIDER: S-EPMC12308281 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature