Outcomes following diagnostic laparoscopy in patients with peritoneal carcinomatosis deemed ineligible for cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) due to disease burden.

ABSTRACT:

Introduction

While cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) can improve overall survival (OS) for patients with peritoneal carcinomatosis from appendiceal or colorectal cancer, some patients are ineligible for CRS/HIPEC due to disease burden. This paper characterizes outcomes for patients who are evaluated by diagnostic laparoscopy (DL) and deemed ineligible for CRS/HIPEC.

Methods

Medical records were retrospectively reviewed for patients who underwent DL and deemed ineligible for CRS/HIPEC (1/1/2009-1/1/2024). Date of death was confirmed using public obituaries. Treatment course/causes of death are summarized by descriptive statistics and OS by Kaplan-Meier analysis.

Results

124 patients were included. Median Peritoneal Cancer I

SUBMITTER: Smith PM 

PROVIDER: S-EPMC12308341 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature