The Predictive Synthesis of Monodisperse and Biocompatible Gold Nanoparticles.

ABSTRACT: The predictive bottom-up synthesis of monodisperse and biocompatible gold nanoparticles using seed-mediated growth procedures is limited by a lack of mathematical models relating reaction components to the final nanoparticle diameter. In this study, we used unique quantitative analytical methods at the single-nanoparticle level to identify the mathematical relationship between the moles of precursor ionic gold and the moles of nanoparticle seeds to synthesize monodisperse gold nanoparticles within ~5% of the target diameter in the ~10 to 120 nm size range. We investigated two commonly used gold nanoparticle syntheses, i.e., the formation of (i) citrate-coated, and (ii) cetyltrimethylammonium chloride (CTAC)-coated gold nanoparticles. Additionally, we developed a surface engineering approac

SUBMITTER: Frickenstein AN 

PROVIDER: S-EPMC12308639 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature