Population-Level Impact of Human Papillomavirus Vaccination on the Incidence of Genital Warts in Sweden.

ABSTRACT:

Background

Sweden introduced human papillomavirus (HPV) vaccination in 2006 via opportunistic, subsidized, catch-up, and school-based programs. Notably, genital warts (GW) are the first observable clinical outcome following HPV-6/11 infection, the strains targeted by vaccination. We aim to assess the incidence of GW in Sweden and its change throughout vaccination programs.

Methods

This ecological study used Swedish registers to obtain national population data and cases of GW from 2006 to 2018 in 15- to 44-year-old men and women. We used Poisson models to estimate GW incidence change after vaccination compared to a prevaccination period, stratified by age and sex, and incidence change of GW in birth cohorts eligible for vaccination compared to a prevaccination cohort. Finally

SUBMITTER: Astorga Alsina AM 

PROVIDER: S-EPMC12308650 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature