Nickel Ferrite Nanoparticles for In Vivo Multimodal Magnetic Resonance and Magnetic Particle Imaging.

ABSTRACT: Magnetic nanoparticles have been at the center of biomedical research for decades, primarily for their applications in magnetic resonance imaging (MRI) and magnetic particle imaging (MPI). Superparamagnetic particles, typically based on iron oxide crystals, are effective in both modalities, although each requires distinct magnetic properties for optimal performance. We investigated the performance of nanoparticles based on a nickel-substituted ferrite core and compared them to standard maghemite iron oxide nanoparticles. We synthesized γ-Fe₂O₃ and Ni _x Fe_2-x O₃ nanoparticles and coated them with a statistical copolymer poly-(N,N-dimethylacrylamide-co-acrylic acid). In vitro testing included X-ray diff

SUBMITTER: Herynek V 

PROVIDER: S-EPMC12308752 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature