Poly(propylene fumarate)/hydroxyapatite nanocomposite/black phosphorus nanosheet phosphate composites for enhanced bone repair.

ABSTRACT:

Background

Bone defects due to trauma, infections, congenital malformations, and tumor resection remain significant health challenges. The polymethyl methacrylate (PMMA) bone cement's limitations in orthopedic applications arise from its lack of bioactivity and the toxicity of its monomers. Hydroxyapatite (HA) cement is widely used for bone reconstruction despite its inherent brittleness. Biodegradable poly(propylene fumarate) (PPF) is recognized for its exceptional performance in addressing these bone defects and providing adequate mechanical support. Black phosphorus (BP) nanosheets (BPNs) have attracted attention due to their unique puckered honeycomb lattice, broad absorption spectrum, high specific surface area, excellent antibacterial properties, and tunable bandgap. In this

SUBMITTER: Huang X 

PROVIDER: S-EPMC12309012 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature