A Novel Peel to Prevent Post-Inflammatory Hyperpigmentation After CO₂ Resurfacing for Acne Scars.

ABSTRACT:

Background

Atrophic acne scars are a common dermatological concern, often requiring fractional carbon dioxide (CO₂) laser resurfacing for effective treatment. However, in darker skin types (Fitzpatrick III-V), the high risk of post-inflammatory hyperpigmentation (PIH) remains a significant limitation, affecting treatment outcomes.

Aims

This study evaluates the efficacy of a novel pre- and post-treatment peel in reducing PIH following fractional CO₂ laser resurfacing, particularly in higher Fitzpatrick skin types. The primary outcome was the incidence and severity of PIH, while secondary outcomes included healing time and changes in acne scar grading.

Method

Twenty-nine patients underwent fractional CO₂ laser resurfacing, with the study

SUBMITTER: Hang X 

PROVIDER: S-EPMC12309148 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature