Association between coffee intake and serum α-Klotho levels in adults: a population-based study.

ABSTRACT:

Background

Coffee is widely consumed in the US, linked to various health benefits, including reduced adiposity. α-Klotho is a circulating protein linked to the aging processes, associated with greater longevity, and confers protective effects against cardiovascular disease, chronic kidney disease, and neurodegenerative disorders. This study investigates the association between coffee (total, caffeinated, and decaffeinated) intake and serum α-Klotho (SαKl) levels.

Methods

Data from 9,811 participants aged 40-79 years from the National Health and Nutrition Examination Survey (2007-2016) were analyzed. Coffee intake was assessed using 24-h dietary recalls in the Food and Nutrient Database for Dietary Studies. SαKl levels were measured using enzyme-linked immunosorbent assay. Mu

SUBMITTER: Tang X 

PROVIDER: S-EPMC12309175 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature