Cardiometabolic risk phenotypes and chronic kidney disease incidence in older adults: a nationwide longitudinal cohort study.

ABSTRACT:

Background

There is mixed evidence for an association between cardiometabolic risk factors and chronic kidney disease risk (CKD). This study aimed to determine whether different latent classes of cardiometabolic conditions were associated with chronic kidney disease risk.

Method

Data from 7,195 participants in the China Health and Retirement Longitudinal Study (CHARLS) were analyzed. Latent class analysis was performed using data on obesity, high-density lipoprotein cholesterol, triglyceride, hypertension, diabetes, arthritis or rheumatism, and systemic inflammatory conditions and heart disease. Confounder-adjusted multiple logistic regressions were conducted to estimate CKD incidence by cardiometabolic latent classes. Sensitivity analyses were performed across cross-section

SUBMITTER: Zeng Z 

PROVIDER: S-EPMC12309190 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature