Updated cancer mortality among uranium miners on the Colorado Plateau: interactions of radon exposure with smoking and temporal factors.

ABSTRACT:

Objectives

Understanding of long-term lung cancer risks from radon decay products (RDP) exposure derives largely from studies of uranium miners. We aimed to compare mortality for lung and other cancers to the general population, to estimate excess absolute rate (EAR) and excess relative rate (ERR) from RDP exposure, and to estimate the joint effects of RDP and cigarette smoking in extended follow-up of a cohort of 4137 male uranium miners from the US Colorado Plateau.

Methods

We extended mortality follow-up through 2016 and re-evaluated RDP exposure against original work history and mine records. We calculated standardised mortality ratios (SMRs) compared with a regional population, evaluated EAR of lung cancer mortality using standardised rate ratios and modelled ERR using

SUBMITTER: Schubauer-Berigan MK 

PROVIDER: S-EPMC12309519 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature