Burden of Chronic Health Conditions Among People With HIV and Common Non-AIDS-Defining Cancers.

ABSTRACT:

Background

With advances in antiretroviral therapy, aging people with HIV (PWH) are increasingly at risk for non-AIDS-defining cancers (NADCs) and chronic morbidities. This study examines whether PWH with NADCs face a higher risk of new-onset chronic health conditions compared with those without cancer.

Patients and methods

We conducted a retrospective cohort study using data from the CFAR (Centers for AIDS Research) Network of Integrated Clinical Systems (CNICS) for PWH enrolled between 1995 and 2018 from 8 US academic institutions. We included PWH with the 5 most common NADCs: anal cancer, non-small cell lung cancer (NSCLC), prostate cancer, classic Hodgkin lymphoma (HL), and hepatocellular carcinoma (HCC). A 1:2 matching for each NADC subgroup was performed based on age,

SUBMITTER: Goyal G 

PROVIDER: S-EPMC12309724 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature