ACE2 Receptor Usage across Animal Species by SARS-CoV-2 Variants.

ABSTRACT: We analyzed the receptor-binding activity and infectivity of 6 representative SARS-CoV-2 lineages in cell lines expressing angiotensin-converting enzyme 2 proteins from 54 different animal species. All viruses demonstrated infectivity in a broad range of species. Susceptible animal species could serve as natural reservoirs or intermediate hosts for SARS-CoV-2.

SUBMITTER: Hatta M 

PROVIDER: S-EPMC12309770 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature