Myocardial perfusion mapping with intra-arterial spin labeling: Optimization of the labeling efficiency.

ABSTRACT:

Purpose

Intra-arterial spin labeling (iASL) applies a labeling pulse from a transmit coil at the tip of the catheter for regional myocardial perfusion measurements during MR-guided catheterizations. This study investigates the labeling efficiency of catheter-mounted coils under varying conditions to enable robust iASL measurements.

Methods

The labeling efficiency was assessed by analytical calculations, numerical simulations, and in vitro measurements at 3 T. Analytical solutions were provided for various simplified B1+$$ {B}_1^{+} $$ field distributions, and a numerical simulation was used to calculate B1+$$ {B}_1^{+} $$ for different catheter coil designs using the Biot-Savart Law. Using these B1+$$ {B}_1^{+} $$ fields, the RF excitation of the blood magnetization flowing

SUBMITTER: Spreter F 

PROVIDER: S-EPMC12309878 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature